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Next-generation tissue expansion method improves neural imaging

The glory of tissue expansion technologies is that when structures, such as proteins that build nerve cell connections, are too small for a microscope to resolve, clever chemistry can make everything bigger and easier to see. But sometimes the chemical bonds involved form right where fluorescent antibody labels must attach to proteins to make them visible. Now a team of MIT researchers has solved the problem, demonstrating vast improvements in imaging the structure of neural connections with standard confocal microscopes. Read More

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